MALT1 Polyclonal Antibody for Human(Homo sapiens) | EIAab.comMALT1 Polyclonal Antibody for Human(Homo sapiens)

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Index > Protein center > MALT1(Gene name) > Human

MALT1 (Gene name),

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Protein name ), MALT1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MALT1(MLT);

Protein name:

Mucosa-associated lymphoid tissue lymphoma translocation protein 1;

Alternative:

Paracaspase;MALT lymphoma-associated translocation;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Binds through its Ig-like domains to BCL10. Forms oligomers which bind to TRAF6.

Function:

Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.

Subcellular Location:

Cytoplasm perinuclear region Nucleus Shuttles between the nucleus and cytoplasm. Found in perinuclear structures together with BCL10.

Protein Attributes:

Sequence length:

824

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

824:

SNVPVETTDE | IPFSFSDRLR | ISEK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.601217

String:

Q9UDY8

MIM:

604860

KEGG:

hsa:10892

Pfam:

PF00656

SMR:

Q9UDY8

Pfam:

PF00047

STRING:

9606.ENSP00000319279

Uniprot:

Q9UDY8

FOR

ELISA Kit for Human Mucosa-associated lymphoid tissue lymphoma translocation protein 1

Cat.:

E15461m

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96T

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ELISA Kit for Human Mucosa-associated lymphoid tissue lymphoma translocation protein 1

Cat.:

E15461h

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Manual:

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MSDS:

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Packing:

96T

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CLIA Kit for Human Mucosa-associated lymphoid tissue lymphoma translocation protein 1

Cat.:

U15461h

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MSDS:

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Packing:

96T

CLIA Kit for Human Mucosa-associated lymphoid tissue lymphoma translocation protein 1

Cat.:

U15461m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Mucosa-associated lymphoid tissue lymphoma translocation protein 1

Cat.:

P15461Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Mucosa-associated lymphoid tissue lymphoma translocation protein 1

Cat.:

P15461Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human Mucosa-associated lymphoid tissue lymphoma translocation protein 1

Protein for Human Mucosa-associated lymphoid tissue lymphoma translocation protein 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas."
Dierlamm J. , Baens M. , Wlodarska I. , Stefanova-Ouzounova M. , Hernandez J.M. , Hossfeld D.K. , De Wolf-Peeters C. , Hagemeijer A. , Van den Berghe H. , Marynen P.
Blood93:3601-3609(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);CHROMOSOMAL TRANSLOCATION
2.

"A novel gene, MALT1 at 18q21, is involved in t(11;18)(q21;q21) found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue."
Akagi T. , Motegi M. , Tamura A. , Suzuki R. , Hosokawa Y. , Suzuki H. , Ota H. , Nakamura S. , Morishima Y. , Taniwaki M. , Seto M.
Oncogene18:5785-5794(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);CHROMOSOMAL TRANSLOCATION
3.

"Identification of paracaspases and metacaspases. Two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma."
Uren A.G. , O'Rourke K. , Aravind L. , Pisabarro M.T. , Seshagiri S. , Koonin E.V. , Dixit V.M.
Mol. Cell6:961-967(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);CHROMOSOMAL TRANSLOCATION
tissue: Kidney.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: B-cell.
5.

"The full-ORF clone resource of the German cDNA consortium."
Bechtel S. , Rosenfelder H. , Duda A. , Schmidt C.P. , Ernst U. , Wellenreuther R. , Mehrle A. , Schuster C. , Bahr A. , Bloecker H. , Heubner D. , Hoerlein A. , Michel G. , Wedler H. , Koehrer K. , Ottenwaelder B. , Poustka A. , Wiemann S. , more...
BMC Genomics8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 598-824
tissue: Testis.
6.

"API1-MALT1-MLT is involved in mucosa-associated lymphoid tissue lymphoma with t(11;18).(q21;q21)."
Suzuki H. , Motegi M. , Akagi T. , Hosokawa Y. , Seto M.
Blood94:3270-3271(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING
7.

"API2-MALT1 chimeric transcripts involved in mucosa-associated lymphoid tissue type lymphoma predict heterogeneous products."
Motegi M. , Yonezumi M. , Suzuki H. , Suzuki R. , Hosokawa Y. , Hosaka S. , Kodera Y. , Morishima Y. , Nakamura S. , Seto M.
Am. J. Pathol.156:807-812(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL TRANSLOCATION
8.

"Bcl10 and MALT1, independent targets of chromosomal translocation in MALT lymphoma, cooperate in a novel NF-kappa B signaling pathway."
Lucas P.C. , Yonezumi M. , Inohara N. , McAllister-Lucas L.M. , Abazeed M.E. , Chen F.F. , Yamaoka S. , Seto M. , Nunez G.
J. Biol. Chem.276:19012-19019(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF CYS-464
9.

"The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes."
Sun L. , Deng L. , Ea C.-K. , Xia Z.-P. , Chen Z.J.
Mol. Cell14:289-301(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: OLIGOMERIZATION;INTERACTION WITH TRAF6;MUTAGENESIS OF GLU-653 AND GLU-806
10.

"Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO."
Zhou H. , Wertz I. , O'Rourke K. , Ultsch M. , Seshagiri S. , Eby M. , Xiao W. , Dixit V.M.
Nature427:167-171(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS A UBIQUITIN LIGASE
11.

"MALT1 contains nuclear export signals and regulates cytoplasmic localization of BCL10."
Nakagawa M. , Hosokawa Y. , Yonezumi M. , Izumiyama K. , Suzuki R. , Tsuzuki S. , Asaka M. , Seto M.
Blood106:4210-4216(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;NUCLEAR EXPORT SIGNAL
12.

"The proteolytic activity of the paracaspase MALT1 is key in T cell activation."
Rebeaud F. , Hailfinger S. , Posevitz-Fejfar A. , Tapernoux M. , Moser R. , Rueda D. , Gaide O. , Guzzardi M. , Iancu E.M. , Rufer N. , Fasel N. , Thome M.
Nat. Immunol.9:272-281(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
13.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-135;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
14.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
15.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
16.

"A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency."
Jabara H.H. , Ohsumi T. , Chou J. , Massaad M.J. , Benson H. , Megarbane A. , Chouery E. , Mikhael R. , Gorka O. , Gewies A. , Portales P. , Nakayama T. , Hosokawa H. , Revy P. , Herrod H. , Le Deist F. , Lefranc G. , Ruland J. , more...
J. Allergy Clin. Immunol.132:151-158(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT IMD12 ILE-89

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